Mary MacDougall, PhD

macdougall@uthscsa.edu

Associate Dean for Research and Professor

University of Texas Health Science Center at San Antonio

(see )

• Craniofacial development
• Dental genetic diseases
• Tooth formation
• Matrix biomineralization
• Tissue engineering
• Dental materials

Transdentinal induction of tertiary dentin.

Gene expression regulation during odontogenesis.

Candidate genes for DG1 and ADAI.

Dental Stem induced tooth regeneration.

Institutional Research Training Grant.

Papagerakis P, MacDougall M, Bailleul-Forestier I, Oboeuf M, Berdal A. Expression and developmental regulation of amelogenin in odontoblasts. Bone (in press).

MacDougall, M. Dental structural diseases mapping to human chromosome 4q21. Conn. Tissue Res. (in press).

Feng, J., Zhang, J., Dallas, S., Chen, S., Lu, Y., Owen, M., Harris, S., and MacDougall, M. Dentin Matrix protein 1 Gene is a target molecular of Cbfa1 in bone. J. Bone and Min. Res. (in press).

Papagerakis, P., Berdel, A., Mesbah, M., Peuchmaur, M., Malaval, L., Nydegger, J., Simmer, J. and MacDougall, M. Investigation of ostoeocalcin, osteonectin, and dentin sialophosphrotein in developing human teeth. Bone 30:377-385, 2002.

MacDougall, M., Simmons, D., Gu, T.T., and Dong, J. MEPE/OF45 a new dentin/bone matrix protein and candidate gene for dentin diseases mapping to chromosome 4q21. Conn. Tissue Res. 43:320-330,2002.

Chen, S., Gu, T.T., Sreenath, T., Kulkarni, A.B., Karsenty, G., and MacDougall, M. Spatial expression of Cbfa1/Runx2 isoforms in teeth and characterization of binding sites in the DSPP gene. Conn. Tissue Res. 43:338-344,2002.

MacDougall, M., Unterbrink, A., Carnes, D., Rani, S., Xianhong, L., Chen, S. Utilization of MO6-G3 Immortalized Odontoblast Cells in Studies Regarding Dentinogenesis. Adv Dental Res. 15:25-29, 2001.

Knight,C., Simmons,D., Gu, T.T., Gluhak-Heinrich,J., Pavlin,D., Zeichner-David, M., MacDougall, M. Cloning, characterization and tissue expressio pattern of mouse Nma/BAMBI during odontogenesis. J Dental Res 80(10):1895-1902, 2001.

Blin-Wakkach, C., Lezot, F., Ghoul-Mazgar, S., Hotton, D., Monteiro, S., Teillaud, C., Pibouin, L., Orester-Cardoso, S., Papagerakis, P., MacDougall, M., Robert, B., and Berdal, A. Endogenous Msx1 antisense transcript:In vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals. Proc Natl Acad Sci USA 98(13):7336-7341, 2001.

MacDougall, M., Simmons, D., Gu, T.T., Forsman-Semb, K., Kärrman Mårdh, C., Mesbah,M., Forest, N., Krebsbach,PH, Yamada,Y and Berdal A. Cloning, characterization and immunolocalization of human ameloblastin. Eur. J. Oral Sci. 108(4):303-310, 2000.

MacDougall, M., Simmons, D., Gu, T.T., and Feng, J, Mouse DSPP Gene: Regulation and Evidence for a Single Gene. Amer Acad Ortho Surgery,317-322, 2000.