Abdullah Karadag, MD, PhD, MSc

akaradag@dir.nidcr.nih.gov

Research Fellow

National Institutes of Health

(see )

• Bone
• Cancer
• Bioinformatics
• SIBLINGs
• Bone sialoprotein
• Osteopontin
• DMP1
• DSPP
• MEPE
• MMP
• Integrin
• Invasion

Regulation of tumor invasion through interactions between BSP, MMP-2 and integrins.

Usage of PNA hybridization probes and FRET technique to quantify mutation rate in McCune Albright Syndrome by application of Real time PCR.

Jain A., Karadag A., Fohr B., Fisher L.W., Fedarko N.S. Three SIBLINGs (Small Integrin-Binding LIgand, N-linked Glycoproteins) Enhance Factor H's Cofactor Activity Enabling MCP-like Cellular Evasion of Complement-mediated Attack. Journal of Biological Chemistry, 277, 13700-13708, 2002.

Fedarko N.S., Jain A., Karadag A., Van Eman M., Fisher L.W. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate and lung cancer. Clinical Cancer Research, 7(12), 4060-4066, 2001.

Karadag A., Scutt A.M., Croucher P.I. Myeloma cells promote the recruitment of osteoblast precursors in vitro: mediation by interleukin-6 (IL-6) and the soluble IL-6 receptor (sIL-6R). Journal of Bone and Mineral Research, 15(10), 1935-1943, 2000.

Karadag A., Oyajobi B.O., Apperley J.F., Russell R.G.G., Croucher P.I. Human myeloma cells promote the production of interleukin 6 by primary human osteoblasts British Journal of Haematology, 108(2), 383-390, 2000.