Luis A. Actis, PhD

actisla@muohio.edu

Associate Professor

Miami University

• Bacterial genetics
• Plasmid biology
• Regulation of gene expression
• Iron acquisition
• Bacterial biofilms
• Bacterial pathogenesis
• Host-pathogen interactions
• Genomics
• Bioinformatics

Genetics of H. aegyptius Brazilian purpuric fever clone (funded by NIAID, R15AI44776-01A1).

Iron uptake in Actinobacillus actinomycetemcomitans (funded by NIDCR, R01DE13657-02).

Dorsey, C. W., Tomaras, A. P., Actis, L. A. Genetic and phenotypic analysis of Acinetobacter baumannii insertion derivatives generated with a Transposome system. Appl. Env. Microbiol. 68, 6353-6360, 2002.

Sarong, R., McGill vary, G., Serrate, D., Actis, L. A., and Tolmasky, M. E. Complete nucleotide sequence of Klebsiella pneumoniae multiresistance plasmid pJHCMW1. Antimicrob. Agents Chemother. 46, 3422-3427, 2002.

Smoot, L. M., France, D. D., McGill vary, G., and Actis, L. A. Genomic analysis of the F3031 Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius by PCR-based subtractive hybridization. Infect. Immun, 70, 2694-2699, 2002.

Tolmasky, M. E., Actis, L. A., and Crosa, J. H. Plasmids, replication. In: Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysts, and Bioseparation, M. C. Flickinger and S. W. Drew, eds. John Wiley and Sons, Inc. N.Y. Online edition, article posted October 15, 2002.

Echenique, J. R., Dorsey, C. W., Patrito, L. C., Petroni, A., Tolmasky, M. E., and Actis, L. A. Acinetobacter baumannii has two genes encoding glutathione-dependent formaldehyde dehydrogenase: evidence for differential regulation in response to iron. Microbiology, 147, 2805-2815, 2001.

Nudel, C., Gonzalez, R., Castañeda, N., Mahler, G., and Actis, L. A. Influence of iron on growth, production of siderophore compounds, membrane proteins, and lipase activity in Acinetobacter calcoaceticus BD413. Microbiol. Res. 155, 263-269, 2001.

Smoot. L. M., Bell, E. C., Crosa, J. H., and Actis, L. A. Detection of Fur and iron transport proteins in the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius. Journal of Medical Microbiology, 48, 629-636, 1999.

Wertheimer, A. M., Verweij, W., Chen. Q., Crosa, L. M., Nagasawa, M., Tolmasky, M. E., Actis, L. A., and Crosa, J. H. Characterization of the angR gene of the fish pathogen Vibrio anguillarum: essential role in virulence. Infect. Immun. 67, 6496-6509, 1999.

Bidinost, C., Wilderman, P. J., Dorsey, C., and Actis, L. A. Analysis of the replication elements of the pMJ101 plasmid from the fish pathogen Vibrio ordalii. Plasmid 42, 20-30, 1999.

Graber, K. R., Smoot, L. M., and Actis, L. A. Expression of iron binding proteins and hemin binding activity in the dental pathogen Actinobacillus actinomycetemcomitans. FEMS Microbiol. Letters, 163, 135-142, 1998.